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Download Alcohol Related Diseases in Gastroenterology by W. K. Lelbach (auth.), Priv. Doz. Dr. med. Helmut Karl PDF

By W. K. Lelbach (auth.), Priv. Doz. Dr. med. Helmut Karl Seitz, Professor Dr. med. Burkhard Kommerell (eds.)

Alcohol abuse ranks one of the commonest and likewise the main serious environmental dangers to human overall healthiness. Its value is heightened through the potential for prevention by means of removal of the behavior, although, hardly exerted. The occurrence of deleterious results on human wellbeing and fitness has relentlessly risen some time past years for a number of components. They contain migration of populations and, quite, elevated urbanization. therefore, in a few components of the area, inhabitants teams formerly spared became concerned, that's additionally re­ flected within the expanding variety of breweries and distilleries within the constructing nations. Social, non secular, and gender-related obstacles to alcohol intake are loosening, and the monetary development of a few segments of populations now permit them to shop for alcoholic drinks. hence the best percent upward push within the usa has lately been in black ladies. kids and youth drink extra alcoholic drinks than ever, and transforming into alcohol abuse by way of pregnant ladies has allow to a rise of the occurrence of the fetal alcohol syndrome. whereas the social and behavioral, together with psychiatric, results of alcoholism are superb, the gastrointestinal and, really, hepatic manifestations are the main common somatic results, and persistent hepatic illness in alcoholics appears to be like to reason the best rate to society. certainly, mortality from liver cirrhosis is taken into account a competent index of alcohol intake in a country.

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Extra resources for Alcohol Related Diseases in Gastroenterology

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Hepatology 4: 165-174 Baraona E, Pirola RC, Lieber CS (1973) The pathogenesis of postprandial hyperlipemia in rats fed ethanol-containing diets. J Clin Invest 52: 296-303 Baraona E, Leo MA, Borowsky SA, Lieber CS (1975) Alcoholic hepatomegaly: accumulation of protein in the liver. Science 190: 794-795 Baraona E, Leo MA, Borowsky SA, Lieber CS (1977) Pathogenesis of alcohol-induced accumulation of protein in the liver. J Clin Invest 50: 546-554 Baraona E, Pikkarainen P, Salaspuro M, Finkelman F, Lieber CS (1980) Acute effects of ethanol on hepatic protein synthesis and secretion in the rat.

Hepatology 4: 165-174 Baraona E, Pirola RC, Lieber CS (1973) The pathogenesis of postprandial hyperlipemia in rats fed ethanol-containing diets. J Clin Invest 52: 296-303 Baraona E, Leo MA, Borowsky SA, Lieber CS (1975) Alcoholic hepatomegaly: accumulation of protein in the liver. Science 190: 794-795 Baraona E, Leo MA, Borowsky SA, Lieber CS (1977) Pathogenesis of alcohol-induced accumulation of protein in the liver. J Clin Invest 50: 546-554 Baraona E, Pikkarainen P, Salaspuro M, Finkelman F, Lieber CS (1980) Acute effects of ethanol on hepatic protein synthesis and secretion in the rat.

Effect of chronic ethanol consumption on the microsomal cytochrome P-450 content and the activity of the microsomal ethanol-oxidizing system (MEOS) in ADH-positive and ADH-negative deer mice. MEOS activity is expressed per cytochrome P-450 content. The data represent mean ± SEM . Note the increase of an "ethanol-specific" band after ethanol consumption in both ADH+ and ADH- deer mice (Shigeta et al. 1984) Increased Tolerance to Drugs and/or Potentiation of Drug Activity Chronic ethanol consumption results in proliferation of the membranes of the smooth endoplasmic reticulum, documented by subfractionation and chemical measurements in micro somes (Ishii et al.

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